Characterization of SpsQ from Staphylococcus pseudintermedius as an affinity chromatography ligand for canine therapeutic antibodies
Coagulase-positive Staphylococci express protein A, which binds to host antibodies, to evade the immune system.Taking advantage of its specific binding to antibodies, protein A from Staphylococcus aureus, which is called SpA, is commonly used as an affinity chromatography ligand for human therapeutic antibodies.However, among four canine IgG subcla